GM102
Overview
GM102 is an oncolytic adenovirus that promotes degradation of tumor extracellular matrix and inhibits pro-metastatic signaling pathways of tumor
Indication: Pancreatic cancer
Development Stage: pre-clinical/preparing phase I clinical trial
Description 1. GM102 effectively degrades tumor extracellular matrix in highly desmoplastic pancreatic tumors to maximize intratumoral virus dispersion, immune cell infiltration, and distribution of cancer treatment modalities 2. GM102 treatment synergistically enhances the therapeutic potential of conventional cancer treatment modalities 3. GM102 effectively inhibits metastasis-associated signaling pathway and suppresses metastasis of tumor