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GM101 is an oncolytic adenovirus induces robust degradation of tumor extracellular matrix, thus resulting in enhanced distribution and dispersion throughout the entirety of tumor

Indication: Solid Tumors

Development Stage: Preparing phase 2 clinical trial

Description 1. Effective degradation of extracellular matrix GM101 maximizes intratumoral virus dispersion, immune cell infiltration, and distribution of cancer treatment modalities 2. GM101 exerts potent pro-apoptotic effect in tumor tissues and effectively inhibits tumor cell proliferation 3. During phase I clinical trial, GM101 induced regression of both the primary tumor (virus-administered lesions) as well as distant metastases

GM101 Data